The use of SSRI during pregnancy and the incidence of psychiatric and neurodevelopmental disorders in childhood: an integrative review
DOI:
https://doi.org/10.20952/jrks4113708Abstract
It is known that depression and anxiety are frequent complications during pregnancy and that such diseases, as well as the use of Selective Serotonin Reuptake Inhibitors (SRIs) such as fluoxetine, sertraline, paroxetine, citalopram and escitalopram can result in harm to both mother and child. The present study aims to discuss the risks and benefits of the need to use these psychotropic drugs during pregnancy and the consequences of psychiatric disorders and neurodevelopmental disorders in offspring. This is an integrative review based on scientific papers with original data. In the results, 13 articles were found in total, and it was observed that the main psychiatric consequences found for the fetus were ASD, ADHD, Maladaptation syndrome and increased possibility of developing future depression and/or anxiety. It was discussed, however, that both maternal psychopathology and the use of SRIS during pregnancy can have negative effects on offspring. In view of this reality, it is necessary to know how to manage the treatment of such pregnant women and the most important when making the decision to start or maintain the use of SRIs is to take into account the severity of the disease, including the risk of suicide, other associated clinical conditions, availability of nonpharmacological therapeutic options and the possible consequences of maternal psychiatric disease for the newborn and the family. Keywords: SSRI during pregnancy; Fetal psychiatric disorders; Maternal Antidepressants.Downloads
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Published
2023-12-30
Issue
Section
Health Sciences